Infections caused by ceftriaxone-susceptible bacteria, or treatment of infections till determination of the causative agent of the infectious disease.

Infections of the respiratory tract: acute and chronic bronchitis, infected bronchiectasis, bacterial pneumonia, lung abscess, postoperative chest infections;

throat and nose infections: sinusitis, tonsillitis, pharyngitis;

urinary tract infections: acute and chronic pyelonephritis, cystitis, asymptomatic bacteriuria;

soft tissues infections: cellulitis, erysipeloid, wound infections;

bone and joint infections: osteomyelitis, septic arthritis;

infections in obstetrics and gynecology: pelvic infectious and inflammatory diseases;

gonorrhea, especially in cases where penicillin is contraindicated;

other infections, including septicemia and meningitis.

Prevention of infectious complications after chest and abdominal surgeries, pelvic surgeries, during vascular, cardiovascular and orthopedic surgeries.

In most cases, cefuroxime monotherapy is effective, but if required, the drug can be used in combination with aminoglycoside antibiotics or with metronidazole (perorally, in suppositories or by injection).

In case of the existing or expected mixed aerobic-anaerobic infection (for example, peritonitis, aspiration pneumonia, abscess of lungs, pelvic organs and brain) and a high probability of such an infection (for example, during the large intestine surgeries or in gynecological surgery), the use of the drug is accepted in combination with metronidazole.

In the treatment of pneumonia and exacerbation of chronic bronchitis, cefuroxime can be administered before oral administration of cefuroxime axetil, if required.