Cefotaxime + Water for injection
General properties
Antibacterials for systemic use. Other beta-lactam antibacterials. Third-generation cephalosporins. Cefotaxime. Antibacterials for systemic use. Other beta-lactam antibacterials. Third-generation cephalosporins. Cefotaxime. Antibacterials for systemic use. Other beta-lactam antibacterials. Third-generation cephalosporins. Cefotaxime.
For treatment of the following serious infections caused or likely to be caused by microorganisms sensitive to cefotaxime:
- Bacterial pneumonia (cefotaxime is not effective against bacteria that cause atypical pneumonia or against other bacterial strains that can cause atypical pneumonia, including P. aeruginosa - see Section “Pharmacodynamics”).
- Complicated kidney and upper urinary tract infections.
- Serious skin and soft tissue infections.
- Genital tract infections caused by gonococci, especially when the use of penicillin has been ineffective or is not suitable.
- Intra-abdominal infections (including peritonitis): When treating intra-abdominal infections, cefotaxime should be administered in combination with the antibiotic effective against anaerobic bacteria.
- Acute bacterial meningitis (especially caused by H. Influenzae, N. Meningitis, S. pneumonie, E. coli, Klebsiella spp.).
- Lyme disease, or tick borreliosis (in particular stages II and III).
- Bacteremia associated or likely to be associated with one of the listed infections (if the infection is caused by gram-negative bacteria, combination with another appropriate antibiotic is recommended).
- Endocarditis (if the infection is caused by gram-negative bacteria, combination with another appropriate antibiotic is recommended).
For perioperative prevention of infectious complications (before/after surgical operations, in particular on the large and straight intestines (colorectal surgery), on the gastrointestinal tract, prostate gland, in the genitourinary system, obstetric and gynecological operations in patients with a significant risk of postoperative infections).
Official recommendations for the proper use of antimicrobials should be taken into account.
Hypersensitivity to cephalosporin antibiotics and other β-lactam antibiotics.
Contraindications for the use of lidocaine-containing solutions:
- hypersensitivity to lidocaine or another amide local anesthetic;
- atrioventricular blocks without an implanted pacemaker;
- severe heart failure;
- intravenous administration;
- children under the age of 1 year (intramuscular administration).
Pharmaceutical characteristics
White or slightly yellow powder.
Store in original package at a temperature not exceeding 25 °С. Keep out of reach of children. By prescription.
